Parkinson's disease is a progressive disease that progresses with the loss of dopamine-producing cells in the basal ganglia in the brain, which provides the movements and coordination of the muscles.

Who does Parkinson's disease affect?

Generally, the incidence increases with age, genetic transmission is usually 10%. It is more common in men.

What kind of disease is Parkinson's?

In the brain, there are substances that enable communication between brain cells called neurotransmitters. In Parkinson's disease, there is a progressive loss of cells that secrete the neurotransmitter called dopamine.

When the brain sends activation signals that tell muscles to move, it fine-tunes your movements using dopamine-requiring cells. Therefore, dopamine deficiency causes the slow movements and tremors of Parkinson's disease.

What is the difference between Parkinson's disease and Parkinsonism?

Parkinsonism; It covers all diseases with Parkinson's symptoms; Multi-system atrophy, such as Corticobasal degeneration.

What are the symptoms of Parkinson's?

motor symptoms; includes movement-related symptoms

slow movements (bradykinesia); caused by muscle control problem
tremor at rest; occurs while at rest in a steady state. It is seen in 80% of Parkinson's patients.
Muscle stiffness (rigidity); It can be seen as lead pipe hardness or gear wheel hardness.
Unsteady posture and gait balance disorder
small handwriting
mask face sign
difficulty swallowing
Soft speaking voice (hypophony)

Non-motor symptoms;
Autonomic nervous system symptoms
Orthostatic Hypotension (low blood pressure while standing)
Constipation
urinary incontinence
sexual dysfunctions
Depression
Loss of sense of smell
periodic leg movement disorder
REM behavior disorder
restless legs syndrome
Thinking and focusing problems (Parkinson's dementia)